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Netrin-1 acts as a survival factor via its receptors UNC5H and DCC

The membrane receptors DCC and UNC5H have been shown to be crucial for axon guidance and neuronal migration by acting as receptors for netrin-1. DCC has also been proposed as a dependence receptor inducing apoptosis in cells that are beyond netrin-1 availability. Here we show that the netrin-1 recep...

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Autores principales: Llambi, Fabien, Causeret, Frédéric, Bloch-Gallego, Evelyne, Mehlen, Patrick
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC125255/
https://ncbi.nlm.nih.gov/pubmed/11387206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.11.2715
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