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A novel role for the Bcl-2 protein family: specific suppression of the RAD51 recombination pathway
The oncogenic role of Bcl-2 is generally attributed to its protective effect against apoptosis. Here, we show a novel role for Bcl-2: the specific inhibition of the conservative RAD51 recombination pathway. Bcl-2 or Bcl-x(L) overexpression inhibits UV-C-, γ-ray- or mutant p53-induced homologous reco...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125251/ https://ncbi.nlm.nih.gov/pubmed/11350949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.10.2596 |
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