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Characterization of mammalian RAD51 double strand break repair using non-lethal dominant-negative forms
In contrast to yeast RAD51, mammalian mRAD51 is an essential gene. Its role in double strand break (DSB) repair and its consequences on cell viability remain to be characterized precisely. Here, we used a hamster cell line carrying tandem repeat sequences with an I-SceI cleavage site. We characteriz...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC203369/ https://ncbi.nlm.nih.gov/pubmed/10856252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.12.3090 |
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