Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: The role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza

The NS1 protein of influenza A virus contributes to viral pathogenesis, primarily by enabling the virus to disarm the host cell type IFN defense system. We examined the downstream effects of NS1 protein expression during influenza A virus infection on global cellular mRNA levels by measuring express...

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Detalhes bibliográficos
Main Authors: Geiss, Gary K., Salvatore, Mirella, Tumpey, Terrence M., Carter, Victoria S., Wang, Xiuyan, Basler, Christopher F., Taubenberger, Jeffery K., Bumgarner, Roger E., Palese, Peter, Katze, Michael G., García-Sastre, Adolfo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125029/
https://ncbi.nlm.nih.gov/pubmed/12149435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.112338099
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