Multiple label-free biodetection and quantitative DNA-binding assays on a nanomechanical cantilever array

We report a microarray of cantilevers to detect multiple unlabeled biomolecules simultaneously at nanomolar concentrations within minutes. Ligand-receptor binding interactions such as DNA hybridization or protein recognition occurring on microfabricated silicon cantilevers generate nanomechanical be...

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Detalhes bibliográficos
Main Authors: McKendry, Rachel, Zhang, Jiayun, Arntz, Youri, Strunz, Torsten, Hegner, Martin, Lang, Hans Peter, Baller, Marko K., Certa, Ulrich, Meyer, Ernst, Güntherodt, Hans-Joachim, Gerber, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125015/
https://ncbi.nlm.nih.gov/pubmed/12119412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.152330199
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