Lytic replication-associated protein (RAP) encoded by Kaposi sarcoma-associated herpesvirus causes p21(CIP-1)-mediated G(1) cell cycle arrest through CCAAT/enhancer-binding protein-α
Kaposi sarcoma-associated herpesvirus (KSHV) is an oncogenic DNA virus that causes Kaposi sarcoma and AIDS-related primary effusion lymphoma (PEL). Here we show that KSHV lytic cycle replication in PEL cells induces G(1) cell cycle arrest, presumably to facilitate the progression of viral DNA replic...
שמור ב:
| הוצא לאור ב: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2002
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125013/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12145325/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.162352299 |
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