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Lytic replication-associated protein (RAP) encoded by Kaposi sarcoma-associated herpesvirus causes p21(CIP-1)-mediated G(1) cell cycle arrest through CCAAT/enhancer-binding protein-α

Kaposi sarcoma-associated herpesvirus (KSHV) is an oncogenic DNA virus that causes Kaposi sarcoma and AIDS-related primary effusion lymphoma (PEL). Here we show that KSHV lytic cycle replication in PEL cells induces G(1) cell cycle arrest, presumably to facilitate the progression of viral DNA replic...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wu, Frederick Y., Tang, Qi-Qun, Chen, Honglin, ApRhys, Colette, Farrell, Christopher, Chen, Jianmeng, Fujimuro, Masahiro, Lane, M. Daniel, Hayward, Gary S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2002
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC125013/
https://ncbi.nlm.nih.gov/pubmed/12145325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162352299
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