The crystal structure of human CD21: Implications for Epstein–Barr virus and C3d binding

Human complement receptor type 2 (CD21) is the cellular receptor for Epstein–Barr virus (EBV), a human tumor virus. The N-terminal two short consensus repeats (SCR1–SCR2) of the receptor interact with the EBV glycoprotein gp350/220 and also with the natural CD21 ligand C3d. Here we present the cryst...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Prota, Andrea E., Sage, David R., Stehle, Thilo, Fingeroth, Joyce D.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2002
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124999/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12122212/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.162360499
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