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High-resolution SNP mapping by denaturing HPLC

With the availability of complete genome sequences, new rapid and reliable strategies for positional cloning become possible. Single-nucleotide polymorphisms (SNPs) permit the mapping of mutations at a resolution not amenable to classical genetics. Here we describe a SNP mapping procedure that relie...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Nairz, Knud, Stocker, Hugo, Schindelholz, Benno, Hafen, Ernst
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124979/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12149455/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.162136299
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