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High-resolution SNP mapping by denaturing HPLC

With the availability of complete genome sequences, new rapid and reliable strategies for positional cloning become possible. Single-nucleotide polymorphisms (SNPs) permit the mapping of mutations at a resolution not amenable to classical genetics. Here we describe a SNP mapping procedure that relie...

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Detalhes bibliográficos
Main Authors: Nairz, Knud, Stocker, Hugo, Schindelholz, Benno, Hafen, Ernst
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC124979/
https://ncbi.nlm.nih.gov/pubmed/12149455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162136299
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