Nitric oxide-induced genotoxicity, mitochondrial damage, and apoptosis in human lymphoblastoid cells expressing wild-type and mutant p53
Nitric oxide (NO(•)) is mutagenic and, under appropriate conditions of exposure, also induces apoptosis in many in vitro and in vivo experimental models. Biochemical and cellular mechanisms through which NO(•) induces apoptosis are incompletely understood, but involve p53/mitochondria-dependent sign...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2002
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124920/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12136132/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.162356399 |
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