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Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase

The heterodimeric Elongin BC complex has been shown to interact in vitro and in cells with a conserved BC-box motif found in an increasing number of proteins including RNA polymerase II elongation factor Elongin A, suppressor of cytokine signaling (SOCS)-box proteins, and the von Hippel–Lindau tumor...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Brower, Christopher S., Sato, Shigeo, Tomomori-Sato, Chieri, Kamura, Takumi, Pause, Arnim, Stearman, Robert, Klausner, Richard D., Malik, Sohail, Lane, William S., Sorokina, Irina, Roeder, Robert G., Conaway, Joan Weliky, Conaway, Ronald C.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124918/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12149480/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.162424199
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