Nitric oxide is consumed, rather than conserved, by reaction with oxyhemoglobin under physiological conditions

Although irreversible reaction of NO with the oxyheme of hemoglobin (producing nitrate and methemoglobin) is extremely rapid, it has been proposed that, under normoxic conditions, NO binds preferentially to the minority deoxyheme to subsequently form S-nitrosohemoglobin (SNOHb). Thus, the primary re...

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Bibliographic Details
Main Authors: Joshi, Mahesh S., Ferguson, T. Bruce, Han, Tae H., Hyduke, Daniel R., Liao, James C., Rassaf, Tienush, Bryan, Nathan, Feelisch, Martin, Lancaster, Jack R.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2002
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC124916/
https://ncbi.nlm.nih.gov/pubmed/12124398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.152149699
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