Nitric oxide is consumed, rather than conserved, by reaction with oxyhemoglobin under physiological conditions

Although irreversible reaction of NO with the oxyheme of hemoglobin (producing nitrate and methemoglobin) is extremely rapid, it has been proposed that, under normoxic conditions, NO binds preferentially to the minority deoxyheme to subsequently form S-nitrosohemoglobin (SNOHb). Thus, the primary re...

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Detalhes bibliográficos
Main Authors: Joshi, Mahesh S., Ferguson, T. Bruce, Han, Tae H., Hyduke, Daniel R., Liao, James C., Rassaf, Tienush, Bryan, Nathan, Feelisch, Martin, Lancaster, Jack R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC124916/
https://ncbi.nlm.nih.gov/pubmed/12124398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.152149699
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