Human MxA Protein Confers Resistance to Semliki Forest Virus and Inhibits the Amplification of a Semliki Forest Virus-Based Replicon in the Absence of Viral Structural Proteins

Mx proteins form a small family of interferon (IFN)-induced GTPases with potent antiviral activity against various negative-strand RNA viruses. To examine the antiviral spectrum of human MxA in homologous cells, we stably transfected HEp-2 cells with a plasmid directing the expression of MxA cDNA. H...

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Autors principals: Landis, Heinrich, Simon-Jödicke, Angela, Klöti, Andreas, Di Paolo, Claudio, Schnorr, Jens-Jörg, Schneider-Schaulies, Sibylle, Hefti, Hans Peter, Pavlovic, Jovan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1998
Matèries:
Virus-Cell Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC124633/
https://ncbi.nlm.nih.gov/pubmed/9445055
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