Identification of the Murine Mx2 Gene: Interferon-Induced Expression of the Mx2 Protein from the Feral Mouse Gene Confers Resistance to Vesicular Stomatitis Virus

The mouse genome contains two related interferon-regulated genes, Mx1 and Mx2. Whereas Mx1 codes for the nuclear 72-kDa protein that interferes with influenza virus replication after interferon treatment, the Mx2 gene is nonfunctional in all laboratory mouse strains examined, since its open reading...

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izdano v:	J Virol
Principais autores:	Jin, Hee Kyung, Takada, Ayato, Kon, Yasuhiro, Haller, Otto, Watanabe, Tomomasa
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1999
Teme:	Pathogenesis and Immunity
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112536/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10233954/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.6.4925-4930.1999
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