Identification of Highly Attenuated Mutants of Simian Immunodeficiency Virus

Deletion mutants of the pathogenic clone of simian immunodeficiency virus isolate 239 (SIVmac239) were derived that are missing nef, vpr, and upstream sequences (US) in the U3 region of the LTR (SIVmac239Δ3), nef, vpx, and US (SIVmac239Δ3x), and nef, vpr, vpx, and US (SIVmac239Δ4). These multiply de...

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Detalhes bibliográficos
Main Authors: Desrosiers, Ronald C., Lifson, Jeffrey D., Gibbs, James S., Czajak, Susan C., Howe, Anita Y. M., Arthur, Larry O., Johnson, R. Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Viral Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC124623/
https://ncbi.nlm.nih.gov/pubmed/9445045
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