Identification of Highly Attenuated Mutants of Simian Immunodeficiency Virus

Deletion mutants of the pathogenic clone of simian immunodeficiency virus isolate 239 (SIVmac239) were derived that are missing nef, vpr, and upstream sequences (US) in the U3 region of the LTR (SIVmac239Δ3), nef, vpx, and US (SIVmac239Δ3x), and nef, vpr, vpx, and US (SIVmac239Δ4). These multiply de...

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Detalles Bibliográficos

Publicado en:	J Virol
Autores principales:	Desrosiers, Ronald C., Lifson, Jeffrey D., Gibbs, James S., Czajak, Susan C., Howe, Anita Y. M., Arthur, Larry O., Johnson, R. Paul
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1998
Materias:	Viral Pathogenesis and Immunity
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124623/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9445045/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.2.1431-1437.1998
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