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Selection of Virus Variants and Emergence of Virus Escape Mutants after Immunization with an Epitope Vaccine

In this report, we assessed the evolution of the cytotoxic T-lymphocyte (CTL) response induced by an epitope vaccine. In two macaques immunized with a mixture of lipopeptides derived from simian immunodeficiency virus (SIV) Nef and Gag proteins, CTL responses were directed against the same, single e...

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Detalhes bibliográficos
Main Authors: Mortara, Lorenzo, Letourneur, Franck, Gras-masse, Helene, Venet, Alain, Guillet, Jean-Gerard, Bourgault-Villada, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC124619/
https://ncbi.nlm.nih.gov/pubmed/9445041
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