Oral Immunization with Recombinant Norwalk Virus-Like Particles Induces a Systemic and Mucosal Immune Response in Mice

Recombinant Norwalk virus-like particles (rNV VLPs) produced in insect cells were evaluated as an oral immunogen in CD1 and BALB/c mice by monitoring rNV-specific serum total and subclass immunoglobulin G (IgG) and intestinal IgA responses. Dose and kinetics of response were evaluated in the presenc...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Ball, Judith M., Hardy, Michele E., Atmar, Robert L., Conner, Margaret E., Estes, Mary K.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Viral Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124613/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9445035/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.2.1345-1353.1998
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