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Molecular Characterization of a Nondemyelinating Variant of Daniel’s Strain of Theiler’s Virus Isolated from a Persistently Infected Glioma Cell Line

Wild-type Daniel’s strain of Theiler’s virus (wt-DA) induces a chronic demyelination in susceptible mice which is similar to multiple sclerosis. A variant of wt-DA (designated DA-P12) generated during the 12th passage of persistent infection of a G26-20 glioma cell line failed to persist and induce...

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Detalhes bibliográficos
Main Authors: Lin, Xiaoqi, Sato, Shigeru, Patick, Amy K., Pease, Larry R., Roos, Raymond P., Rodriguez, Moses
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC124604/
https://ncbi.nlm.nih.gov/pubmed/9445026
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