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Human Papillomavirus Oncoproteins E6 and E7 Independently Abrogate the Mitotic Spindle Checkpoint

The E6 and E7 genes of the high-risk human papillomavirus (HPV) types encode oncoproteins, and both act by interfering with the activity of cellular tumor suppressor proteins. E7 proteins act by associating with members of the retinoblastoma family, while E6 increases the turnover of p53. p53 has be...

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Bibliografske podrobnosti
izdano v:J Virol
Principais autores: Thomas, Jennifer T., Laimins, Laimonis A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1998
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124587/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9445009/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.2.1131-1137.1998
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