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Resistance to Virus Infection Conferred by the Interferon-Induced Promyelocytic Leukemia Protein

The interferon (IFN)-induced promyelocytic leukemia (PML) protein is specifically associated with nuclear bodies (NBs) whose functions are yet unknown. Two of the NB-associated proteins, PML and Sp100, are induced by IFN. Here we show that overexpression of PML and not Sp100 induces resistance to in...

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Bibliographic Details
Main Authors: Chelbi-Alix, Mounira K., Quignon, Frédérique, Pelicano, Luis, Koken, Marcel H. M., de Thé, Hugues
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC124576/
https://ncbi.nlm.nih.gov/pubmed/9444998
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