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Inhibition of mitochondrial respiration by endogenous nitric oxide: A critical step in Fas signaling
We have found that activation of human adult T cell leukemia (Jurkat) cells with anti-Fas Ab leads, in a concentration-dependent manner, to an early burst of production of nitric oxide (NO), which inhibits cell respiration. This results in mitochondrial hyperpolarization, dependent on the hydrolysis...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2002
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC124394/ https://ncbi.nlm.nih.gov/pubmed/12077295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092259799 |
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