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Blockade of vascular endothelial growth factor receptor-3 signaling inhibits fibroblast growth factor-2-induced lymphangiogenesis in mouse cornea

Vascular endothelial growth factor receptor-3 (VEGFR-3) is a major mediator of lymphangiogenesis. Recently, VEGFR-3 ligands, VEGF-C, and VEGF-D were reported to promote tumor lymphangiogenesis and lymphatic metastasis, and these processes were inhibited by blocking of the VEGFR-3-signaling pathway....

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Kubo, Hajime, Cao, Renhai, Bräkenhielm, Ebba, Mäkinen, Taija, Cao, Yihai, Alitalo, Kari
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2002
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On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124390/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12070340/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.062040199
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