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Hsp90 enables Ctf13p/Skp1p to nucleate the budding yeast kinetochore

Binding of CBF3, a protein complex consisting of Ndc10p, Cep3p, Ctf13p, and Skp1p, to the centromere DNA nucleates kinetochore formation in budding yeast. Here, we investigate how the Ctf13p/Skp1p complex becomes competent to form the CBF3-centromere DNA complex. As revealed by mass spectrometry, Ct...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Stemmann, Olaf, Neidig, Anke, Köcher, Thomas, Wilm, Matthias, Lechner, Johannes
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124320/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12084919/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.082223899
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