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Autoregulation of a bacterial σ factor explored by using segmental isotopic labeling and NMR

Bacterial σ factors combine with the catalytic core RNA polymerase to direct the process of transcription initiation through sequence-specific interactions with the −10 and −35 elements of promoter DNA. In the absence of core RNA polymerase, the DNA-binding function of σ is autoinhibited by its own...

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Detalhes bibliográficos
Main Authors: Camarero, Julio A., Shekhtman, Alexander, Campbell, Elizabeth A., Chlenov, Mark, Gruber, Tanja M., Bryant, Donald A., Darst, Seth A., Cowburn, David, Muir, Tom W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC124302/
https://ncbi.nlm.nih.gov/pubmed/12084914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.132033899
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