The phytoestrogen genistein induces thymic and immune changes: A human health concern?

Use of soy-based infant formulas and soy/isoflavone supplements has aroused concern because of potential estrogenic effects of the soy isoflavones genistein and daidzein. Here we show that s.c. genistein injections in ovariectomized adult mice produced dose-responsive decreases in thymic weight of u...

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Bibliographic Details
Main Authors: Yellayi, Srikanth, Naaz, Afia, Szewczykowski, Melissa A., Sato, Tomomi, Woods, Jeffrey A., Chang, Jongsoo, Segre, Mariangela, Allred, Clint D., Helferich, William G., Cooke, Paul S.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2002
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC124301/
https://ncbi.nlm.nih.gov/pubmed/12032332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102650199
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