Placental overgrowth in mice lacking the imprinted gene Ipl

The Ipl (Tssc3) gene lies in an extended imprinted region of distal mouse chromosome 7, which also contains the Igf2 gene. Expression of Ipl is highest in placenta and yolk sac, where its mRNA is derived almost entirely from the maternal allele. Ipl encodes a small cytoplasmic protein with a pleckst...

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Bibliographic Details
Main Authors: Frank, Dale, Fortino, Weiwei, Clark, Lorraine, Musalo, Raymond, Wang, Wenxian, Saxena, Anjana, Li, Chi-Ming, Reik, Wolf, Ludwig, Thomas, Tycko, Benjamin
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2002
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC124258/
https://ncbi.nlm.nih.gov/pubmed/12032310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.122039999
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