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Placental overgrowth in mice lacking the imprinted gene Ipl

The Ipl (Tssc3) gene lies in an extended imprinted region of distal mouse chromosome 7, which also contains the Igf2 gene. Expression of Ipl is highest in placenta and yolk sac, where its mRNA is derived almost entirely from the maternal allele. Ipl encodes a small cytoplasmic protein with a pleckst...

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Autores principales: Frank, Dale, Fortino, Weiwei, Clark, Lorraine, Musalo, Raymond, Wang, Wenxian, Saxena, Anjana, Li, Chi-Ming, Reik, Wolf, Ludwig, Thomas, Tycko, Benjamin
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC124258/
https://ncbi.nlm.nih.gov/pubmed/12032310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.122039999
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