Sequence survey of receptor tyrosine kinases reveals mutations in glioblastomas

It is now clear that tyrosine kinases represent attractive targets for therapeutic intervention in cancer. Recent advances in DNA sequencing technology now provide the opportunity to survey mutational changes in cancer in a high-throughput and comprehensive manner. Here we report on the sequence ana...

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Détails bibliographiques
Auteurs principaux: Rand, Vikki, Huang, Jiaqi, Stockwell, Tim, Ferriera, Steve, Buzko, Oleksandr, Levy, Samuel, Busam, Dana, Li, Kelvin, Edwards, Jennifer B., Eberhart, Charles, Murphy, Kathleen M., Tsiamouri, Alexia, Beeson, Karen, Simpson, Andrew J. G., Venter, J. Craig, Riggins, Gregory J., Strausberg, Robert L.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2005
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1242336/
https://ncbi.nlm.nih.gov/pubmed/16186508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507200102
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