Sequence survey of receptor tyrosine kinases reveals mutations in glioblastomas

It is now clear that tyrosine kinases represent attractive targets for therapeutic intervention in cancer. Recent advances in DNA sequencing technology now provide the opportunity to survey mutational changes in cancer in a high-throughput and comprehensive manner. Here we report on the sequence ana...

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Detalhes bibliográficos
Main Authors: Rand, Vikki, Huang, Jiaqi, Stockwell, Tim, Ferriera, Steve, Buzko, Oleksandr, Levy, Samuel, Busam, Dana, Li, Kelvin, Edwards, Jennifer B., Eberhart, Charles, Murphy, Kathleen M., Tsiamouri, Alexia, Beeson, Karen, Simpson, Andrew J. G., Venter, J. Craig, Riggins, Gregory J., Strausberg, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1242336/
https://ncbi.nlm.nih.gov/pubmed/16186508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507200102
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