Sequence survey of receptor tyrosine kinases reveals mutations in glioblastomas

It is now clear that tyrosine kinases represent attractive targets for therapeutic intervention in cancer. Recent advances in DNA sequencing technology now provide the opportunity to survey mutational changes in cancer in a high-throughput and comprehensive manner. Here we report on the sequence ana...

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Hlavní autoři: Rand, Vikki, Huang, Jiaqi, Stockwell, Tim, Ferriera, Steve, Buzko, Oleksandr, Levy, Samuel, Busam, Dana, Li, Kelvin, Edwards, Jennifer B., Eberhart, Charles, Murphy, Kathleen M., Tsiamouri, Alexia, Beeson, Karen, Simpson, Andrew J. G., Venter, J. Craig, Riggins, Gregory J., Strausberg, Robert L.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2005
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1242336/
https://ncbi.nlm.nih.gov/pubmed/16186508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507200102
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