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The radioresistance kinase TLK1B protects the cells by promoting repair of double strand breaks

BACKGROUND: The mammalian protein kinase TLK1 is a homologue of Tousled, a gene involved in flower development in Arabidopsis thaliana. The function of TLK1 is not well known, although knockout of the gene in Drosophila or expression of a dominant negative mutant in mouse cells causes loss of nuclea...

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Autors principals: Sunavala-Dossabhoy, Gulshan, Balakrishnan, Sri Kripa, Sen, Siddhartha, Nuthalapaty, Sam, De Benedetti, Arrigo
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1242231/
https://ncbi.nlm.nih.gov/pubmed/16156902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-6-19
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