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Reciprocal role of cyclins and cyclin kinase inhibitor p21(WAF1/CIP1 )on lymphocyte proliferation, allo-immune activation and inflammation

BACKGROUND: Immune activation that results due to the aberrant proliferation of lymphocytes leads to inflammation and graft rejection in organ transplant recipients. We hypothesize that the cell cycle control and inflammation are parallel events, inhibition of cellular proliferation by cyclin kinase...

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Bibliografske podrobnosti
Glavni avtor: Khanna, Ashwani K
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1242230/
https://ncbi.nlm.nih.gov/pubmed/16176581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-6-22
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