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Anthracyclines, proteasome activity and multi-drug-resistance
BACKGROUND: P-glycoprotein is responsible for the ATP-dependent export of certain structurally unrelated compounds including many chemotherapeutic drugs. Amplification of P-glycoprotein activity can result in multi-drug resistance and is a common cause of chemotherapy treatment failure. Therefore, t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1242219/ https://ncbi.nlm.nih.gov/pubmed/16159384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-5-114 |
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