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Effects of Natural Selection on Interpopulation Divergence at Polymorphic Sites in Human Protein-Coding Loci

To develop new strategies for searching for genetic associations with complex human diseases, we analyzed 2784 single-nucleotide polymorphisms (SNPs) in 396 protein-coding genes involved in biological processes relevant to cancer and other complex diseases, with respect to gene diversity within samp...

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Библиографические подробности
Главные авторы: Hughes, Austin L., Packer, Bernice, Welch, Robert, Bergen, Andrew W., Chanock, Stephen J., Yeager, Meredith
Формат: Artigo
Язык:Inglês
Опубликовано: Genetics Society of America 2005
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1242184/
https://ncbi.nlm.nih.gov/pubmed/15911586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.037077
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