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Progesterone Antagonizes the Permissive Action of Estradiol on Tumor Necrosis Factor-α-Induced Apoptosis of Anterior Pituitary Cells

We previously reported that TNF-α-induced apoptosis of lactotropes is estrogen dependent and predominant at proestrus. Here we observed that TNF-α (50 ng/ml) failed to induce apoptosis of anterior pituitary cells from ovariectomized rats cultured in the presence of progesterone (10(−6) m). However,...

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Bibliografiset tiedot
Päätekijät: Candolfi, M., Jaita, G., Zaldivar, V., Zárate, S., Ferrari, L., Pisera, D., Castro, M. G., Seilicovich, A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1242177/
https://ncbi.nlm.nih.gov/pubmed/15528300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2004-1276
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