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TUMOR-TARGETED GENE DELIVERY USING POLY(ETHYLENE GLYCOL)-MODIFIED GELATIN NANOPARTICLES: IN VITRO AND IN VIVO STUDIES
PURPOSE: To develop safe and effective systemically-administered non-viral gene therapy vectors for solid tumors, DNA-containing poly(ethylene glycol)-modified (PEGylated) gelatin nanoparticles were fabricated and evaluated in vitro and in vivo. EXPERIMENTAL METHODS: Reporter plasmid DNA encoding fo...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1242175/ https://ncbi.nlm.nih.gov/pubmed/15948039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-005-4590-3 |
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