The expression of the ubiquitin ligase subunit Cks1 in human breast cancer

INTRODUCTION: Loss of the cell-cycle inhibitory protein p27(Kip1 )is associated with a poor prognosis in breast cancer. The decrease in the levels of this protein is the result of increased proteasome-dependent degradation, mediated and rate-limited by its specific ubiquitin ligase subunits S-phase...

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Autores principales: Slotky, Merav, Shapira, Ma'anit, Ben-Izhak, Ofer, Linn, Shai, Futerman, Boris, Tsalic, Medy, Hershko, Dan D
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1242136/
https://ncbi.nlm.nih.gov/pubmed/16168119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1278
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