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Membrane Trafficking of Heterotrimeric G Proteins via the Endoplasmic Reticulum and Golgi

Membrane targeting of G-protein αβγ heterotrimers was investigated in live cells by use of Gα and Gγ subunits tagged with spectral mutants of green fluorescent protein. Unlike Ras proteins, Gβγ contains a single targeting signal, the CAAX motif, which directed the dimer to the endoplasmic reticulum....

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Bibliographic Details
Main Authors: Michaelson, David, Ahearn, Ian, Bergo, Martin, Young, Stephen, Philips, Mark
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC124159/
https://ncbi.nlm.nih.gov/pubmed/12221133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-02-0095
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