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The Major Core Protein P4a (A10L Gene) of Vaccinia Virus Is Essential for Correct Assembly of Viral DNA into the Nucleoprotein Complex To Form Immature Viral Particles

The vaccinia virus (VV) A10L gene codes for a major core protein, P4a. This polypeptide is synthesized at late times during viral infection and is proteolytically cleaved during virion assembly. To investigate the role of P4a in the virus life cycle and morphogenesis, we have generated an inducer-de...

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Detalhes bibliográficos
Main Authors: Heljasvaara, Ritva, Rodríguez, Dolores, Risco, Cristina, Carrascosa, José L., Esteban, Mariano, Rodríguez, Juan Ramón
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114294/
https://ncbi.nlm.nih.gov/pubmed/11390580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.13.5778-5795.2001
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