The Major Core Protein P4a (A10L Gene) of Vaccinia Virus Is Essential for Correct Assembly of Viral DNA into the Nucleoprotein Complex To Form Immature Viral Particles

The vaccinia virus (VV) A10L gene codes for a major core protein, P4a. This polypeptide is synthesized at late times during viral infection and is proteolytically cleaved during virion assembly. To investigate the role of P4a in the virus life cycle and morphogenesis, we have generated an inducer-de...

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Bibliographic Details
Main Authors: Heljasvaara, Ritva, Rodríguez, Dolores, Risco, Cristina, Carrascosa, José L., Esteban, Mariano, Rodríguez, Juan Ramón
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC114294/
https://ncbi.nlm.nih.gov/pubmed/11390580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.13.5778-5795.2001
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