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DNA Repair and Transcriptional Effects of Mutations in TFIIH in Drosophila Development

Mutations in XPB and XPD TFIIH helicases have been related with three hereditary human disorders: xeroderma pigmentosum, Cockayne syndrome, and trichothiodystrophy. The dual role of TFIIH in DNA repair and transcription makes it difficult to discern which of the mutant TFIIH phenotypes is due to def...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Merino, Carlos, Reynaud, Enrique, Vázquez, Martha, Zurita, Mario
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC124156/
https://ncbi.nlm.nih.gov/pubmed/12221129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-02-0087
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