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α4β1 Integrin Regulates Lamellipodia Protrusion via a Focal Complex/Focal Adhesion-independent Mechanism

α4β1 integrin plays an important role in cell migration. We show that when ectopically expressed in Chinese hamster ovary cells, α4β1 is sufficient and required for promoting protrusion of broad lamellipodia in response to scratch-wounding, whereas α5β1 does not have this effect. By time-lapse micro...

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書目詳細資料
Main Authors: Pinco, Karen A., He, Wei, Yang, Joy T.
格式: Artigo
語言:Inglês
出版: The American Society for Cell Biology 2002
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC124153/
https://ncbi.nlm.nih.gov/pubmed/12221126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.02-05-0086
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