Prediction of rodent nongenotoxic carcinogenesis: evaluation of biochemical and tissue changes in rodents following exposure to nine nongenotoxic NTP carcinogens.

We studied nine presumed nongenotoxic rodent carcinogens, as defined by the U.S. National Toxicology Program (NTP), to determine their ability to induce acute or subacute biochemical and tissue changes that may act as useful predictors of nongenotoxic rodent carcinogenesis. The chemicals selected in...

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Detalhes bibliográficos
Main Authors: Elcombe, Clifford R, Odum, Jenny, Foster, John R, Stone, Susan, Hasmall, Susan, Soames, Anthony R, Kimber, Ian, Ashby, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1240799/
https://ncbi.nlm.nih.gov/pubmed/11940454
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