Production of Sepiapterin in Escherichia coli by Coexpression of Cyanobacterial GTP Cyclohydrolase I and Human 6-Pyruvoyltetrahydropterin Synthase

Synechocystis sp. strain PCC 6803 GTP cyclohydrolase I and human 6-pyruvoyltetrahydropterin synthase were coexpressed in Escherichia coli. The E. coli transformant produced sepiapterin, which was identified by high-performance liquid chromatography and enzymatically converted to dihydrobiopterin by...

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Detaylı Bibliyografya

Yayımlandı:	Appl Environ Microbiol
Asıl Yazarlar:	Woo, Hyun Joo, Kang, Jee Yun, Choi, Yong Kee, Park, Young Shik
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	American Society for Microbiology (ASM) 2002
Konular:	Physiology and Biotechnology
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123912/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12039779/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.68.6.3138-3140.2002
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