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Participation of both Gab1 and Gab2 in the activation of the ERK/MAPK pathway by epidermal growth factor

Three members of Gab family docking proteins, Gab1, Gab2 and Gab3, have been identified in humans. Previous studies have found that the hepatocyte growth factor preferentially utilizes Gab1 for signalling, whereas Bcr-Abl selectively signals through Gab2. Gab1–SHP2 interaction has been shown to medi...

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Détails bibliographiques
Auteurs principaux: Meng, Songshu, Chen, Zhengming, Munoz-Antonia, Teresita, Wu, Jie
Format: Artigo
Langue:Inglês
Publié: Portland Press Ltd. 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1237148/
https://ncbi.nlm.nih.gov/pubmed/15952937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050229
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