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Cloning and characterization of a cAMP-specific phosphodiesterase (TbPDE2B) from Trypanosoma brucei

Here we report the cloning, expression, and characterization of a cAMP-specific phosphodiesterase (PDE) from Trypanosoma brucei (TbPDE2B). Using a bioinformatic approach, two different expressed sequence tag clones were identified and used to isolate the complete sequence of two identical PDE genes...

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Sparad:
I publikationen:Proc Natl Acad Sci U S A
Huvudupphov: Rascón, Ana, Soderling, Scott H., Schaefer, Jonathan B., Beavo, Joseph A.
Materialtyp: Artigo
Språk:Inglês
Utgiven: National Academy of Sciences 2002
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123713/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11930017/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.002031599
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