Desensitization of μ-opioid receptor-evoked potassium currents: Initiation at the receptor, expression at the effector
Many G protein-coupled receptor-mediated responses desensitize within minutes. Sustained stimulation of μ-opioid receptors (MORs), which primarily signal through G(i/o) proteins, leads to activation and subsequent desensitization of G protein-coupled inwardly rectifying potassium (GIRK) currents. We...
Збережено в:
| Опубліковано в:: | Proc Natl Acad Sci U S A |
|---|---|
| Автори: | , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
National Academy of Sciences
2002
|
| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123706/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11917119/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.072075399 |
| Теги: |
Немає тегів, Будьте першим, хто поставить тег для цього запису!
|