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Akt2 Phosphorylates Ezrin to Trigger NHE3 Translocation and Activation

Initiation of Na(+)-glucose cotransport in intestinal absorptive epithelia causes NHE3 to be translocated to the apical plasma membrane, leading to cytoplasmic alkalinization. We reported recently that this NHE3 translocation requires ezrin phosphorylation. However, the kinase that phosphorylates ez...

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Detalhes bibliográficos
Main Authors: Shiue, Harn, Musch, Mark W., Wang, Yingmin, Chang, Eugene B., Turner, Jerrold R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1237052/
https://ncbi.nlm.nih.gov/pubmed/15531580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M409471200
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