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Evolutionary conservation suggests a regulatory function of AUG triplets in 5′-UTRs of eukaryotic genes
By comparing sequences of human, mouse and rat orthologous genes, we show that in 5′-untranslated regions (5′-UTRs) of mammalian cDNAs but not in 3′-UTRs or coding sequences, AUG is conserved to a significantly greater extent than any of the other 63 nt triplets. This effect is likely to reflect, pr...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1236974/ https://ncbi.nlm.nih.gov/pubmed/16186132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki847 |
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